Naltrexone is a well-researched medication originally developed in the 1970s and approved in the 1980s for helping people reduce harmful drinking. Its effectiveness was demonstrated through decades of clinical trials, including work by Dr. John Sinclair, whose research showed that drinking while taking Naltrexone could gradually retrain the brain’s reward pathways. Instead of relying on willpower, Naltrexone works at a neurological level by blocking the endorphin “reward” released when alcohol is consumed. Over time, this leads to fewer cravings and a natural decline in drinking.
Effective for Social Drinkers
While Naltrexone has often been associated with people who struggle with heavy or dependent drinking, modern evidence shows it can be extremely effective for social and casual drinkers as well. Many people who drink more than they intend to – or find themselves stuck in a cycle of habit drinking – benefit from how gently Naltrexone reduces the desire for “one more.” It helps individuals stay in control, maintain moderation, and avoid the escalation of drinking patterns without forcing abstinence.

Reduced, Appropriate Dose
At DrinkLessMethod.co.uk, we specialise in supporting social and casual drinkers, which is why we uniquely recommend starting with 25mg instead of the traditional 50mg dose. Research shows that lower doses can still produce a strong therapeutic effect for people without dependence, while significantly reducing the likelihood of side effects such as nausea, headaches, or fatigue. Many clients find 25mg easier to tolerate, allowing them to stay consistent and experience steady progress with minimal disruption.
Our approach is designed to make alcohol reduction accessible, comfortable, and tailored to real-world drinking habits. By combining Naltrexone science with a lower-dose method, social drinkers can effectively reshape their relationship with alcohol—while still enjoying life, social events, and a balanced lifestyle.
