What is Naltrexone?

We have out together a series of resources to help you to understand the key medication behind the Drink Less Method and the Sinclair Method which has inspired our approach.

Scientist using digital tablet in laboratory for research

The Sinclair Method (TSM)

Pioneered by  Dr. John David Sinclair, the method uses 50mg doses of Naltrexone to temporarily block the brainโ€™s reward response from alcohol consumption. The Drink Less Method is influenced by the Sinclair Method, but starts with titration doses of the medication to help minimise side effects.


What is Nalmefene?

A Powerful Alternative for People Who Do Not Respond to Naltrexone Many people looking to reduce their alcohol consumption will have heard of naltrexone, one of the most widely studied medications used in alcohol-related treatment pathways. However, what happens if naltrexone doesnโ€™t provide the response you were hoping for?ย 


The Drink Less Test

The test aims to help you with the question of whether your drinking is causing you a problem. This test will tell you if the Drink Less Method is right for you.


Alcohol Units Explained

A unit of alcohol is not one drink. It is a measure of pure alcohol. And once you begin calculating properly, the totals often surprise people.

Know your alcohol Units graphic

Dry January Support to Help You Drink Less and Feel Better

Dry January is your first big break from alcohol or part of a longer journey to drink less, weโ€™re here to help you succeed with personalised guidance, motivation, and practical tools.

RemiVida Lady

Read Our Recent Blog Posts

  • Does the Sinclair Method Work?

    Does the Sinclair Method Work?

    What Does the Evidence Really Show? If you’ve been researching ways to drink less, you may already have encountered The Sinclair Method, naltrexone and claims of a 78% success rate. It sounds impressive. But does the Sinclair Method really work? And how strong is the evidence behind those claims? The answer is more interesting than…

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  • Sober October vs Drinking Less

    Sober October vs Drinking Less

    Which Approach Can Help You Change Your Drinking Habits? October has become a popular time to reconsider our relationship with alcohol. For many people, that means Sober October: taking a complete break from alcohol for the month. It’s a simple challenge with an equally simple ruleโ€”don’t drink during October. But complete abstinence isn’t everyone’s goal.…

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  • What Happens to Your Liver When You Drink Less Alcohol?

    What Happens to Your Liver When You Drink Less Alcohol?

    What happens when you drink less? Reducing alcohol is one of the most positive health decisions many people can make. Whether you are cutting down gradually, taking more alcohol-free days or working towards stopping completely, drinking less gives your body a chance to move away from the constant pressure of processing alcohol. Your liver plays…

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  • Can Your Liver Recover After Drinking?

    Can Your Liver Recover After Drinking?

    What to Know When Youโ€™re Cutting Down Can your liver recover after drinking? This is one of the most common questions people ask when they start drinking less: โ€œHave I damaged my liver โ€” and can it recover?โ€ The honest answer is: it depends. The liver has a remarkable ability to improve when alcohol intake…

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  • Liver Support for People Drinking Less: What Actually Matters?

    Liver Support for People Drinking Less: What Actually Matters?

    Liver support without the detox nonsense Search for liver support online and you will find hundreds of products promising detoxes, cleanses, flushes and resets. The problem is that many of these claims sound more dramatic than they really are. If you are drinking less alcohol, you do not need a scary โ€œdetoxโ€ message. You need…

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