What is Naltrexone?

We have out together a series of resources to help you to understand the key medication behind the Drink Less Method and the Sinclair Method which has inspired our approach.

Scientist using digital tablet in laboratory for research

The Sinclair Method (TSM)

Pioneered by  Dr. John David Sinclair, the method uses 50mg doses of Naltrexone to temporarily block the brainโ€™s reward response from alcohol consumption. The Drink Less Method is influenced by the Sinclair Method, but starts with titration doses of the medication to help minimise side effects.


What is Nalmefene?

A Powerful Alternative for People Who Do Not Respond to Naltrexone Many people looking to reduce their alcohol consumption will have heard of naltrexone, one of the most widely studied medications used in alcohol-related treatment pathways. However, what happens if naltrexone doesnโ€™t provide the response you were hoping for?ย 


The Drink Less Test

The test aims to help you with the question of whether your drinking is causing you a problem. This test will tell you if the Drink Less Method is right for you.


Alcohol Units Explained

A unit of alcohol is not one drink. It is a measure of pure alcohol. And once you begin calculating properly, the totals often surprise people.

Know your alcohol Units graphic

Dry January Support to Help You Drink Less and Feel Better

Dry January is your first big break from alcohol or part of a longer journey to drink less, weโ€™re here to help you succeed with personalised guidance, motivation, and practical tools.

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