What is Naltrexone?

For your second or repeat prescription from the Drink Less Method, you will be required to complete an additional consultation, covering changes to your health, medication and drinking habits, prior to issuing a repeat prescription.

Naltrexone can be ordered from this website after carrying out a thorough consultation. Your answers will be reviewed by the in-house clinician and, if there are no further questions from them, you will be issued with a private prescription to order your first series of Naltroxene . This order is for a two month supply – the first supply at a lower dose to be sure of no serious side effects.

Yes, it’s completely legal. The 50mg Naltrexone products are fully licensed in the UK for alcohol and opioid dependency.

None of the manufacturers currently have applied for (or obtained) a license for a lower dose, not that the medicine is unregulated or illegal.

Off label medicines are very common and legal in the UK and often called ‘specials’ and used by qualified clinicians to prescribe them when, in their judgment, it’s likely to help and is safe for you. They don’t require an NHS prescription, so you just pay the price listed on this website plus any postage fees. It does not mean the treatment is “unapproved” or shady.

Some people feel changes within the first week, while for others it may take a little longer. The benefits tend to build over time as drinking becomes less appealing. Real results appear for most subjects after four weeks of use.

No. Naltrexone is non-addictive and does not cause a “high.” It simply reduces the rewarding effect of alcohol so you’re more in control of your choices.

No. Unlike some treatments that require total abstinence, naltrexone is designed to support moderation. You can still enjoy a drink if you’d like—many people just find it easier to stop after one or two.

Naltrexone blocks the brain’s opioid receptors, which are part of what makes alcohol feel rewarding. With less of that “buzz,” you may find yourself naturally drinking less without having to rely on sheer willpower.

Naltrexone in 50mg capsules is proven in multiple randomised clinical trials to show oral naltrexone helps people with Alcohol Use Disorder to reduce heavy drinking and addiction when combined with psychological support.

Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism

“Eight double-blind placebo-controlled clinical trials in five countries have demonstrated the safety and efficacy of naltrexone as an adjunct in alcoholism treatment. The efficacy depends, however, on how naltrexone is used. Three of the trials tested naltrexone in two ways: (1) with supportive therapy, i.e. support of complete abstinence; (2) with therapy tacitly accepting that relapses may occur and teaching how to cope with them.” Source John David Sinclair

Conclusions: Both naltrexone and nalmefene have proved to be safe, well tolerated, easy to manage, and efficient drugs for the treatment of alcohol dependence disorder (currently known as alcohol use disorder). On the basis of recent controlled clinical trials, nalmefene has been shown to result in a significant reduction of alcohol consumption, thereby representing a new objective that extends the therapeutic possibilities for those patients who do not wish for a continuous abstinence, but rather a reduction of alcohol consumption. Click for Source

Naltrexone is usually taken as a tablet on days when you are planning to have a drink – one hour before normal drinking time. Over time, this steady support can help reduce cravings and make drinking less of a focus in your day-to-day life.